[關(guān)鍵詞]
[摘要]
組學(xué)技術(shù)手段作為新興的高通量分析手段,近年來在中藥的質(zhì)量評(píng)價(jià)、藥理機(jī)制研究等方面得到廣泛應(yīng)用,在黨參Codonopsis Radix的現(xiàn)代化研究中發(fā)揮著重要作用。通過對(duì)以高通量分析為典型特點(diǎn)的組學(xué)技術(shù)在大宗藥材黨參質(zhì)量評(píng)價(jià)、藥理機(jī)制研究及相關(guān)領(lǐng)域的研究現(xiàn)狀進(jìn)行綜述,為組學(xué)技術(shù)在黨參研究中進(jìn)一步拓展完善提供參考依據(jù),促進(jìn)組學(xué)技術(shù)在中藥質(zhì)量評(píng)價(jià)和藥理作用機(jī)制研究領(lǐng)域的深入研究與應(yīng)用。
[Key word]
[Abstract]
As an emerging high-throughput analysis tool, omics technology has been widely used in the quality evaluation and pharmacological mechanism research of traditional Chinese medicine (TCM) in recent years, and play an important role in the modernisation research of Dangshen (Codonopsis Radix). By reviewing the current research status of omics technology, which is typically characterised by high-throughput analysis, in the quality evaluation, pharmacological mechanism, and related fields of the bulk medicinal material Codonopsis Radix, this review aims to provide a reference basis for the further expansion and improvement of omics technology in Codonopsis Radix research, and thereby promoting in-depth research and application of omics technology in the field of quality evaluation and pharmacological mechanism studies of TCM.
[中圖分類號(hào)]
R285
[基金項(xiàng)目]
國(guó)家自然科學(xué)基金資助項(xiàng)目(82160714);甘肅省科技計(jì)劃項(xiàng)目(21JR1RA271);2021年度甘肅高等學(xué)校產(chǎn)業(yè)支撐計(jì)劃項(xiàng)目(2021CYZC-40);甘肅省教育廳2023年高?!皠?chuàng)新之星”項(xiàng)目(2023CXZX-740);甘肅省重點(diǎn)研發(fā)計(jì)劃項(xiàng)目(23YFFA0069);蘭州市科技局校企合作項(xiàng)目(2023-RC-9);甘肅省中醫(yī)藥研究中心開放課題(zyzx-2023-10);蘭州市科技項(xiàng)目(2024-9-78)