[關鍵詞]
[摘要]
組學技術手段作為新興的高通量分析手段,近年來在中藥的質量評價、藥理機制研究等方面得到廣泛應用,在黨參Codonopsis Radix的現(xiàn)代化研究中發(fā)揮著重要作用。通過對以高通量分析為典型特點的組學技術在大宗藥材黨參質量評價、藥理機制研究及相關領域的研究現(xiàn)狀進行綜述,為組學技術在黨參研究中進一步拓展完善提供參考依據(jù),促進組學技術在中藥質量評價和藥理作用機制研究領域的深入研究與應用。
[Key word]
[Abstract]
As an emerging high-throughput analysis tool, omics technology has been widely used in the quality evaluation and pharmacological mechanism research of traditional Chinese medicine (TCM) in recent years, and play an important role in the modernisation research of Dangshen (Codonopsis Radix). By reviewing the current research status of omics technology, which is typically characterised by high-throughput analysis, in the quality evaluation, pharmacological mechanism, and related fields of the bulk medicinal material Codonopsis Radix, this review aims to provide a reference basis for the further expansion and improvement of omics technology in Codonopsis Radix research, and thereby promoting in-depth research and application of omics technology in the field of quality evaluation and pharmacological mechanism studies of TCM.
[中圖分類號]
R285
[基金項目]
國家自然科學基金資助項目(82160714);甘肅省科技計劃項目(21JR1RA271);2021年度甘肅高等學校產業(yè)支撐計劃項目(2021CYZC-40);甘肅省教育廳2023年高?!皠?chuàng)新之星”項目(2023CXZX-740);甘肅省重點研發(fā)計劃項目(23YFFA0069);蘭州市科技局校企合作項目(2023-RC-9);甘肅省中醫(yī)藥研究中心開放課題(zyzx-2023-10);蘭州市科技項目(2024-9-78)