半夏瀉心湯是源自《傷寒雜病論》的經(jīng)典方劑，對多種疾病具有較好的臨床療效。通過系統(tǒng)回顧半夏瀉心湯在不同疾病中的臨床應(yīng)用，并探討其作用機制，發(fā)現(xiàn)半夏瀉心湯通過調(diào)節(jié)炎癥因子、改善胃腸運動功能、調(diào)節(jié)腸道菌群等作用，對胃食管反流病、胃炎、消化性潰瘍、炎癥性腸病等消化系統(tǒng)疾病具有顯著療效。該方劑在循環(huán)系統(tǒng)疾病、皮膚疾病、腫瘤性疾病和婦科疾病等方面也顯示出較好的治療效果。半夏瀉心湯的安全性高、不良反應(yīng)少，適用于個體化治療。未來研究應(yīng)進一步探索其臨床應(yīng)用、有效成分、作用機制和分子靶點，以提高臨床應(yīng)用的科學(xué)性和準確性。

Banxia Xiexin Decoction (半夏瀉心湯) is a traditional Chinese medicine prescription derived from Treatise on Febrile and Miscellaneous Diseases. It has good clinical effect on treating many diseases. By systematically reviewing the clinical applications of Banxia Xiexin Decoction in different diseases and exploring its mechanism of action, it is found that Banxia Xiexin Decoction exerts effects such as regulating inflammatory factors, improving gastrointestinal motility function, and regulating the intestinal flora. It has significant curative effects on digestive system diseases such as gastroesophageal reflux disease, gastritis, peptic ulcer, and inflammatory bowel disease. In addition, the prescription has also shown good therapeutic effect in the fields of circulatory system diseases, skin diseases, neoplastic diseases and gynecological diseases. Banxia Xiexin Decoction has high safety and few adverse reactions, and is suitable for individualized treatment. Future studies should further explore its clinical application, active ingredients, mechanism of action and molecular targets to improve the scientific and accurate clinical application.

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國家自然科學(xué)基金項目（82274412）；國家自然科學(xué)基金項目（82305092）；國家中醫(yī)藥管理局高水平中醫(yī)藥重點學(xué)科建設(shè)項目（zyyzdxk-2023147）；廣東省重點領(lǐng)域研發(fā)項目（2020B1111100001）；湖南省自然科學(xué)基金項目（2023JJ30453）；長沙市自然科學(xué)基金項目（kq2208185）